IRON SUPPLEMENTATION ELIMINATES ANTAGONISTIC INTERACTIONS BETWEEN ROOT-ASSOCIATED BACTERIA


TRIB2 safeguards naive T cell homeostasis during aging

Summary: Naive CD4+ T cells are more resistant to age-related loss than naive CD8+ T cells, suggesting mechanisms that preferentially protect naive CD4+ T cells during aging.Here, we show that TRIB2 is more abundant in naive CD4+ than CD8+ T cells and counteracts quiescence exit by suppressing AKT activation.TRIB2 deficiency increases AKT activity

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Paradoxical sleep deprivation increases plasma endothelin levels

The endothelins (ET-1, 2 and 3) constitute a family of 21 amino acid peptides with potent biological activities.ET-1 is one of the most potent endogenous vasoconstrictors so far identified and its increased concentration in plasma appears to be closely related to the pathogenesis of arterial hypertension as well as to obstructive sleep apnea (OSA).

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Reform and modernization in the Ottoman Empire

The boundaries of the Ottoman Empire span several centuries on a vast expanse, across the ancient continents of the world, with different races, diverse peoples and multiple faiths, and the Ottoman Empire was one of the forces that influenced the course of international politics at the time, and then it was weakened by the political balance and adm

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